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BMJ - British Medical Journal
Children will suffer from changes to US research system
As paediatricians working in the US, we view the changes being made to our healthcare and education systems, research enterprise, and regulatory agencies1 as truly dystopian.The damage is clear to us. The breakdown of information from the Centers for Disease Control and Prevention; unjustified firing of workers from the National Science Foundation, US Department of Agriculture, Food and Drug Administration, and Environmental Protection Agency; decreasing the funding of university research through the National Institutes of Health; dismantling the US Agency for International Development; and withdrawal from the World Health Organization and the Paris Climate Agreement have disproportionately adverse effects on children. Children will suffer from diseases and disabilities that otherwise could be prevented and treated, a dire consequence of policies adopted by the very federal government entrusted with promoting and protecting their health, development, and functioning.Dictators have historically used health as a target to destroy the core strength of their...
Categories: Medical Journal News
Sharp Scratch Episode 131: Are you really listening?
In this episode of Sharp Scratch, the panel got together to discuss the importance of properly listening to patients.The panel was joined by guest Rageshri Dhairyawan to explore how medical students and doctors can work to improve their listening by increasing their awareness of biases that may lead to some groups of patients being dismissed. The episode highlighted the broader implications of not properly hearing patients, including the impact on health equity. The discussion also covered the challenges of dealing with uncertainty and acknowledging the social factors that can affect healthcare outcomes. The episode emphasised the ways in which becoming a better listener as a medical professional can help us to provide more compassionate and holistic care.Rageshri Dhairyawan is a consultant in sexual health and HIV medicine at Barts Health NHS Trust and deputy director of the SHARE Collaborative for Health Equity, Queen Mary University of London. She is author...
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Rising cases of TB and measles in England demand ambitious public health approach, says Harries
Rising cases of tuberculosis (TB) and measles and an intense influenza and respiratory syncytial virus (RSV) season were seen in England in 2024-25, reiterating the fact that “we cannot be complacent,” the outgoing head of the UK Health Security Agency (UKHSA) has said.The agency’s first report on infectious diseases looks at data from 2023 to early 2025 and acknowledges that social mixing, international travel, migration, and vaccine hesitancy following the covid-19 pandemic have contributed to these patterns of infection.1Provisional data for 2024 show that there were 600 new cases of TB in England in 2024, 13% more than in 2023. This followed an 11% increase in cases in 2023, with 4855 notifications of the disease compared with 4380 in 2022.If cases of TB continue to increase on their current trajectory the UK would lose its World Health Organisation low incidence status, warned Jenny Harries, chief executive of the UKHSA, at...
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Aid cuts threaten decades of progress in reducing child deaths and stillbirths, warns UN
Decades of progress in improving childhood survival are being put at risk because of major cuts to aid funding, the United Nations has warned.In a report1 published on 25 March the UN found that the number of children dying globally before their 5th birthday has more than halved from 10.1m in 2000 to 4.8m in 2023. Stillbirths have declined modestly, from 2.9m in 2000 to 1.9m in 2021.2But it warned that these gains are now under threat as major aid donors such as the US have announced funding cuts. Earlier this month the Trump administration permanently cancelled funding for nearly 10 000 projects supporting global health and development, equating to a cut of nearly $60bn in aid spending.3 US cuts to foreign aid have already closed vital child malnutrition services in war torn Sudan.4World Health Organization director general Tedros Adhanom Ghebreyesus said, “In the face of global funding cuts, there...
Categories: Medical Journal News
UK welfare reforms threaten health of the most vulnerable
The chancellor of the exchequer, Rachel Reeves, will set out the UK government’s spending plans in her spring statement on 26 March.1 The consultative green paper, Pathways to Work,2 has already outlined plans to cut several billion from the welfare budget, with the aim of saving £5bn by 2029-30.3 The plans include stricter criteria for personal independence payments (PIP) for people with disabilities; halving incapacity benefit payments under Universal Credit for new claimants; and restriction of incapacity benefit top-ups to those aged 23 years and older.Ministers have argued there is a “moral case” for these cuts, and that “people that can work [should be] able to work.”3 However, the chancellor’s approach is unlikely to achieve this goal for two key reasons. First, high rates of economic inactivity in the UK reflect its almost unique failure among industrialised countries to recover population health after the pandemic,456 which came on top of...
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Are “copycat” compounded weight loss drugs safe?
In the UK more than 3 in every 1000 people are taking glucagon-like peptide-1 (GLP-1) agonist drugs, says Kevin McCarroll, consultant physician and geriatrician at St James Hospital, Dublin.1 Depending on the region, 77-179 in 100 000 people are using the leading GLP-1 drug semaglutide (Ozempic for type 2 diabetes, Wegovy for obesity), he says.1 And these are just the official prescribing figures—anecdotal evidence suggests many are purchasing the drugs from unofficial sources.Growing evidence of the drugs’ efficacy for weight loss2 is fuelling demand worldwide. The number of patients in the US approved for GLP-1 agonist treatment for obesity rose from 190 000 a month in 2021 to 1.8 million in 2024.3 Analysis of the US market shows that 5.2% of women and 4.2% of men with obesity are being prescribed the drugs, although access varies.“The global supply shortage seen in 2024 was at least partly because of a surge...
Categories: Medical Journal News
Medical students call on UK government to “fix our funding”
Medical students from across the UK rallied outside the Department for Education on 19 March to demand adequate financial support.BMA representatives from the Medical Students Committee delivered a letter to Bridget Phillipson, the secretary of state for education, asking the government to “ensure that both undergraduate and graduate students are eligible for the full Student Finance England maintenance loan provision for all years of study,” as well as improving access to funding through the NHS bursary, “including improving the claims process and exploring new sources of funding.”Medical students stop being solely funded by Student Finance England in their fifth year when maintenance loans fall from a maximum of £10 277 to £2670 an academic year. This is then topped up with the NHS bursary of £1020 and a means tested grant of up to £2696 for those outside of London and £3255 for those in London. An additional £86 a...
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Lucy Letby: Families’ lawyers cast doubt on panel’s findings that questioned convictions
Lawyers for families whose babies the nurse Lucy Letby was convicted of killing or assaulting have cast doubt on the findings by an international panel of experts which appear to exonerate her.1The 14 strong panel revealed its conclusion that the deaths were attributable to natural causes or poor medical care at the Countess of Chester Hospital, where Letby worked, at a press conference organised by her barrister, Mark McDonald, last month.2 Letby is serving 15 life terms after being convicted of murdering seven babies and attempting to murder seven others between June 2015 and June 2016.3 McDonald is asking the Criminal Cases Review Commission to send the case back to the Court of Appeal, after Letby’s previous attempts were turned down.In written submissions to the Thirlwall inquiry, the legal team representing several babies’ families, headed by Richard Baker KC, noted that the panel, assembled by the retired Canadian neonatologist Shoo...
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BMA calls for changes to “absurd” pension tax rules as senior doctors reduce hours
The government has been urged to remove the financial barriers to doctors taking on additional work after a BMA survey showed that many consultants and GPs have cut their hours in the past year because of pension tax rules.The BMA’s poll of more than 5000 senior doctors found that many have reduced their work commitments to such a degree that if replicated across the wider workforce it would equate to the loss of around 5400 full time consultants. The BMA highlighted that this is almost 10% of capacity that could be offered to the NHS in England to tackle waiting lists this year. For GP partners, it estimates that the reduction in hours represents a potential loss of around four million appointments.The long standing problem is related to the tapered annual allowance (AA), introduced in 2016, which imposes a limit on how much senior doctors can put into their pension...
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H5N1: UK reports world’s first case in a sheep
The UK has confirmed a case of H5N1 influenza of avian origin in a sheep in Yorkshire, in a world first.The infection in the animal was identified through routine and repeated milk testing, which was enforced after avian influenza was confirmed in captive birds on the same premises. The sheep has now been “humanely culled” and no other cases of avian influenza have been detected in the remaining sheep, the Department for Environment, Food, and Rural Affairs and the Animal and Plant Health Agency have said.“While this is the first time this virus has been reported in a sheep, it is not the first time influenza of avian origin has been detected in livestock in other countries,” the announcement said. “There is no evidence to suggest an increased risk to the nation’s livestock.”In January the UK confirmed a human case of influenza A (H5N1) in a person in the West...
Categories: Medical Journal News
The growing number of prospective doctors given placeholder jobs demands urgent action
The growing number of medical students put on a “placeholder” list after applying for foundation year training raises serious concerns about the capacity and foresight of the UK Foundation Programme Office (UKFPO). In 2024, more than a thousand medical school graduates were left without allocated foundation year training posts and faced a prolonged period of uncertainty while emergency posts were created.1 This has left graduates unable to plan the next steps of their careers and personal lives. Early reports suggest that this year hundreds of students have again been given a placeholder allocation.2The shortage of foundation training posts is indicative of a growing problem, as the number of students graduating from UK medical schools is expected to continue rising.3 This is the harbinger of an emerging workforce crisis. Unless there is an adequately planned, sustained expansion in the number of foundation training posts available in the UK, the placeholder list...
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Confusion between sex and gender identity in official data has dangerous implications, review warns
A growing tendency in official data to ask a person for their gender identity rather than their sex is having serious consequences in some areas of healthcare such as missed cancer screenings and mistakes in blood testing.An independent, government commissioned report1 into the collection of accurate data and statistics on biological sex concluded that public bodies should collect distinct data on both sex and gender identity to ensure that nationally held data are accurate and clear.The report, published by the Department for Science, Innovation, and Technology, sets out a timeline of how survey data have been collected since the 1960s. It shows how the word “gender” started to replace “sex” in some data collection in the 1990s, and in some survey data, gender was defined as “sex” while in others gender was defined as “identity.”The review authors found that from around 2015 the word “gender” started to be understood in...
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Anne Bayley: surgical oncologist who recognised the spread of AIDS in Zambia among heterosexual patients
bmj;388/mar24_9/r574/FAF1faIn 1983 surgeons across East Africa began to compare notes about a new disease, known colloquially as “slim,” which was prevalent across the region. At the time, Anne Bayley was running a clinic at the University Teaching Hospital in Lusaka, Zambia, for patients with endemic Kaposi’s sarcoma, a relatively indolent skin tumour, found mainly in older men.In 1983, however, the number of new cases of Kaposi’s sarcoma doubled to 23—and 13 of these patients (including three women) presented with unusual, more aggressive disease. Eight patients died in less than a year.1 There was also a rise in reports of Kaposi’s sarcoma in the literature, reflecting the emergence of HIV/AIDS among mainly gay men in the West. Bayley realised that HIV was the underlying problem in her patients with aggressive Kaposi’s sarcoma, which she thought implied heterosexual transmission. Not everyone agreed, convinced that it was spread by sex between men.Keeping an...
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ABPI is criticised for lifting Novo Nordisk suspension despite recent breaches
Researchers have criticised the UK drug industry trade association’s decision to restore Novo Nordisk’s membership despite the company being subject to ongoing regulatory breaches during its two year suspension period.In March 2023 the Danish pharmaceutical company, which manufactures the high profile weight loss drugs Ozempic, Saxenda, and Wegovy, was suspended as a member of the Association of the British Pharmaceutical Industry (ABPI) for two years because of “serious breaches” of the organisation’s code of practice.1 The company failed to disclose clearly its sponsorship of a weight management training course for healthcare professionals which included positive information on its obesity drug liraglutide (Saxenda).The ABPI, announcing its decision to reinstate Novo Nordisk’s membership on 17 March, said it was satisfied that the company had made “clear, significant, and sustained improvements” to ensure it properly adheres to strict industry standards.2But academics from the University of Bath told The BMJ that the available evidence—including...
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Near-infrared spectroscopy in perioperative medicine
Near-infrared spectroscopy (NIRS), originally described in 1977, entered clinical practice as a non-invasive method to assess regional tissue oxygenation.1 This monitoring technique was initially used in high risk surgeries to measure cerebral oxygenation in real time. After encouraging results that linked intraoperative NIRS guided, goal directed treatment to improved neurological outcomes in cardiac surgery, NIRS use quickly expanded.234 This increased use has sparked the development of multiple competing clinically approved NIRS monitoring systems, highlighting the substantial market interest in this technology.5Despite the widespread use of NIRS, negative findings from subsequent trials have raised concerns about whether NIRS monitoring truly improves outcomes.678 These concerns have prompted a debate regarding the surgical populations who might benefit from NIRS and the best practices for its use.9 In a linked research paper (doi:10.1136/bmj-2024-082104), Han and colleagues present noteworthy findings from the Bottomline-CS trial, which examined whether perioperative care guided by cerebral and peripheral tissue...
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Combining medicine and mental health: the consultant old age liaison psychiatrist
A love of people and their life stories inspired Raja Badrakalimuthu to specialise in old age psychiatry.“Working with older people, you get to have conversations about their lives,” says Badrakalimuthu, a consultant old age liaison psychiatrist at Royal Surrey County Hospital in Guildford. “Their generation built our society, and we’ve inherited the legacy of their hard work. I find it satisfying to be able to do something for them—to thank them, and show my gratitude.”Old age psychiatry is “the perfect blend of medicine and mental health,” he says. “Older people can have multiple physical conditions and you have to take this into account when diagnosing dementia.”With new dementia drugs becoming incorporated into clinical practice, and new cognitive assessments and scans becoming readily available, “it’s an exciting time to be doing old age psychiatry,” Badrakalimuthu says. Old age psychiatrists also have to be aware of what kind of support is available...
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Trump 2.0—a backwards step for women’s sexual and reproductive rights
Buse and McKee discuss the potential changes to global health directions, funding, and structures under a second Trump administration.1 They note the risk to funding of organisations supporting sexual and reproductive health rights. These include the reinstatement of such policies as the “global gag rule,” in which the US government refuses to fund global non-government organisations who provide, refer, or promote access to abortion.2 This was very damaging under the first Trump administration.3 But changes in health policy direction and funding could also undermine progress in women’s health in other ways such as increased gender based violence, diminished reproductive autonomy, and shifts in societal norms. We would like to discuss this last aspect.An effect of Trump 2.0 will be the emboldening of men and others who share certain perspectives about the role of women in society. The far right slogan, “Your body, my choice,” tweeted by white nationalist Nick Fuentes...
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Art of “holding patient care in general practice” is key to survival of the NHS
Data on hospital beds are important1 but must not eclipse upstream priorities for tackling pressures in the NHS. Strengthening general practice is crucial. This calls for medical educators and NHS leaders who value and promote generalist skills—in particular, the art of “holding patient care in general practice.” “Holding” necessitates meeting patients’ health needs as far as possible entirely within the primary care setting and avoiding premature or unnecessary secondary care involvement or specialist investigations. Community presentations such as self-limiting illnesses, mental health issues, and medically unexplained symptoms infrequently follow a linear diagnostic algorithm. They require a “social-psycho-bio” (rather than a “bio-psycho-social”) perspective that tackles social circumstances, psychological wellbeing, and media driven expectations. Here, learners must be comfortable consulting “in the dark”: navigating patient care through history, examination, incremental management, and safety netting rather than defaulting to sequential clinical tests.2 In low risk populations, excessive investigation begets onward referral from ambiguous...
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Covid-19: Inquiry hears of doctors’ lack of confidence in PPE as ministers defend VIP lane
National PPE approach was focused on hospitalsDanny Mortimer, chief executive of NHS Employers and deputy chief executive of the NHS Confederation, told the inquiry that there was a lack of availability of personal protective equipment (PPE) in every part of the health service, but that it was particularly severe in general practices, community settings, and mental health services.1 He said members of the confederation believed that the national approach to PPE was focused on the acute sector. He cited a confederation survey of GPs in early 2020 in which 83% of respondents reported that they didn’t have proper access to masks with filters and 73% reported a lack of access to goggles and visors.Giving evidence on 18 March, Mortimer highlighted problems with the availability of specific equipment such as masks fitted with respirators. “There was particular concern about the availability of equipment that could fit different types of faces, whether...
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PROBAST+AI: an updated quality, risk of bias, and applicability assessment tool for prediction models using regression or artificial intelligence methods
In healthcare, prediction models or algorithms (hereafter referred to as prediction models) estimate the probability of a health outcome for individuals. In the diagnostic setting—including screening and monitoring—the model typically aims to predict or classify the presence of a particular outcome, such as a disease or disorder. In the prognostic setting the model aims to predict a future outcome—typically health related—in patients with a diagnosis of a particular disease or disorder, or in the general population. The primary use of a prediction model in healthcare is to support individual healthcare counselling and shared decision making on, for example, subsequent medical testing, referral to another healthcare professional or facility, treatment, discharge from hospital, or lifestyle changes. For example, the tool QR4 predicts the probability of developing a cardiovascular event within the next 10 years and informs whether individuals should undergo changes to their lifestyle or be prescribed drugs.1 Prediction models are...
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